Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 184
interventional 142
Observational 39
Registry 3

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 39
Device 34
Drug|placebo 34
Procedure 24
Device|Procedure 2
Drug|Other 2
Other 2
Behavioral 1
Biological|placebo 1
Device|Drug|Procedure 1
Drug|Other|placebo 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 40
NA 18
Korea, Republic of 8
Canada 5
Germany 5
Japan 5
Italy 4
United Kingdom 4
China 3
France 3
Sweden 3
United States|Canada 3
United States|Puerto Rico 3
Cuba 2
Netherlands 2
Turkey 2
United States|Canada|Puerto Rico 2
Austria 1
Austria|Belgium|France|Germany|Israel|Italy|Netherlands|Poland|Spain 1
Belgium 1
Belgium|Czechia|France|Germany|Hungary|Italy|Latvia|Lithuania|Romania|Ukraine|United Kingdom 1
Brazil 1
Denmark 1
Egypt 1
Finland|Austria|Belgium|Bulgaria|Czech Republic|Germany|Hungary|Italy|Lithuania|Netherlands|Norway|Poland|Portugal|Spain|Sweden|United Kingdom 1
France|Germany|Korea, Republic of|Netherlands 1
France|Israel|Russian Federation|United Kingdom 1
Hong Kong 1
India|Czech Republic|Hungary|Romania|Russian Federation|Ukraine 1
Israel 1
Mexico 1
Norway 1
Poland 1
Spain 1
Switzerland 1
Taiwan|Australia|Austria|Belgium|Bulgaria|Canada|Czechia|Denmark|Finland|Germany|Hungary|Ireland|Italy|Korea, Republic of|Lithuania|Netherlands|Norway|Poland|Portugal|Slovakia|Spain|Sweden|United Kingdom 1
United States|Belgium|Brazil|Chile|Czechia|Hungary|Italy|Poland|South Africa 1
United States|Belgium|Brazil|Chile|Czechia|Hungary|Poland|South Africa 1
United States|Belgium|Italy|Spain 1
United States|Brazil|Italy|Poland|South Africa|United Kingdom 1
United States|Bulgaria|China|Czechia|Israel|Malaysia|New Zealand|Singapore|South Africa 1
United States|Bulgaria|Czechia|Hungary|Latvia|Lithuania|Poland|Romania|Ukraine 1
United States|China|Czechia|Finland|Hong Kong|Japan|Mexico|Norway|Poland|Russian Federation|South Africa|Thailand|Turkey 1
United States|Czechia|Japan|Russian Federation|Ukraine 1
United States|Guatemala|Mexico 1
United States|Mexico 1
United States|South Africa|Brazil|Chile|Czechia|Hungary|Italy|Poland 1

Sites per Study

Site_count Study_Count
1 80
2 15
3 3
4 4
5 3
6 1
8 3
9 2
11 3
16 2
23 1
25 2
27 1
28 1
38 1
46 1
49 2
56 1
63 1
64 1
87 1
96 1
97 1
103 1
105 2
110 1
116 1
124 1
127 1
140 1
148 1
157 1
219 1

Phase

Phase Study_Count
N/A 52
Phase 3 39
Phase 2 22
Phase 4 14
Phase 1 8
Phase 2/Phase 3 4
Phase 1/Phase 2 2
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 37
2 57
3 24
4 8
5 6
6 1
7 1
8 1
11 1
NA 6

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 30 3.00000 10.00000 11.0 16.00000 36 2.0000 12.00000
1st Qu. 30 31.50000 22.50000 15.5 38.50000 39 91.5000 30.00000
Median 30 52.00000 30.00000 20.0 52.00000 70 241.0000 50.00000
Mean 30 69.07692 35.71429 20.0 98.18182 94 288.9744 64.53846
3rd Qu. 30 81.00000 46.00000 24.5 110.00000 125 432.5000 60.00000
Max. 30 444.00000 73.00000 29.0 567.00000 200 1272.0000 214.00000

Trial Group Type

group_type Group_Count
Experimental 211
Active Comparator 48
Placebo Comparator 38
Other 10
No Intervention 9
NA 6
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Parallel Assignment 92
Single Group Assignment 45
Crossover Assignment 3
NA 2

Primary Purpose

primary_purpose Study_Count
Treatment 120
Prevention 6
Diagnostic 4
Supportive Care 4
NA 4
Health Services Research 3
Other 1

Observational Studies

Studies by Country

Country Study_Count
United States 12
Spain 4
Italy 3
Taiwan 3
Canada 2
NA 2
Turkey 2
Belgium 1
Brazil 1
China 1
Egypt 1
France 1
France|New Caledonia 1
Germany|Netherlands|Switzerland|United Kingdom 1
Japan 1
Mexico 1
Poland 1
United States|Australia|Chile|Czechia|Georgia|Hungary|Poland 1

Sites per Study

Site_count Study_Count
1 32
2 1
3 1
6 1
10 1
20 1
23 1
63 1

Enrollment Metrics

Measure Observational
Min 15.00
1st Qu 52.50
Median 130.50
Mean 42875.18
3rd Qu 645.00
Max 1600000.00

Observation Model

observational_model Study_Count
Cohort 18
Case-Only 9
Case-Control 5
Case Control 4
NA 2
Other 1

Time Perspective

time_perspective Study_Count
Prospective 23
Retrospective 11
Cross-Sectional 3
Other 2

Registries

Studies by Country

Country Study_Count
Germany 1
Norway 1
United States 1

Sites per Study

Site_count Study_Count
1 1
6 1
9 1

Enrollment Metrics

Measure Registries
Min 80.000
1st Qu 90.000
Median 100.000
Mean 1091.333
3rd Qu 1597.000
Max 3094.000

Registry Model

observational_model Study_Count
Cohort 2
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 3

Follow-up

target_duration Study_Count
2 Years 1
3 Years 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03400956 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 4) https://ClinicalTrials.gov/show/NCT03400956 Active, not recruiting Bayer 2019-03-23
NCT03400943 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 3) https://ClinicalTrials.gov/show/NCT03400943 Active, not recruiting Bayer 2019-06-09
NCT03400826 Effects of Simvastatin on Uterine Leiomyoma Size https://ClinicalTrials.gov/show/NCT03400826 Recruiting Johns Hopkins University 2024-01-01
NCT03369600 Characterisation of Uterine Fibroid Tissue Stiffness https://ClinicalTrials.gov/show/NCT03369600 Enrolling by invitation University of Ottawa 2020-07-31
NCT04295109 Comparison of the Effects of Fentanyl, Oxycodone, Butorphanol on Gastrointestinal Function https://ClinicalTrials.gov/show/NCT04295109 Recruiting The First Affiliated Hospital with Nanjing Medical University 2020-07-31
NCT03342859 Mode of Action Study of Vilaprisan and Ulipristal Acetate in Patients With Uterine Fibroids for Whom Surgery is Planned https://ClinicalTrials.gov/show/NCT03342859 Active, not recruiting Bayer 2018-12-17
NCT03328260 High Intensity Focused Ultrasound in Uterine Myoma https://ClinicalTrials.gov/show/NCT03328260 Completed Seoul National University Hospital 2018-08-31
NCT03323905 Single Arm Study Using the Symphony – MRI Guided Focused Ultrasound System for the Treatment of Leiomyomas https://ClinicalTrials.gov/show/NCT03323905 Recruiting Sunnybrook Health Sciences Centre 2020-09-30
NCT03317795 Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03317795 Recruiting Mayo Clinic 2020-06-30
NCT03271489 Long-Term Safety Study of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women https://ClinicalTrials.gov/show/NCT03271489 Active, not recruiting AbbVie 2023-08-18
NCT03194646 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03194646 Active, not recruiting Bayer 2019-05-10
NCT03103087 LIBERTY 2: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03103087 Active, not recruiting Myovant Sciences GmbH 2019-07-01
NCT03072446 Uterine Fibroid Embolization (UFE) for Symptomatic Fibroids: Comparison of Gel-Bead to Commonly Used Embolic Agents. https://ClinicalTrials.gov/show/NCT03072446 Completed University Hospital Southampton NHS Foundation Trust 2018-06-30
NCT03070951 Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03070951 Active, not recruiting ObsEva SA 2019-09-16
NCT03070899 Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03070899 Active, not recruiting ObsEva SA 2020-03-31
NCT03049735 LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03049735 Active, not recruiting Myovant Sciences GmbH 2019-04-29
NCT03009812 Transverse vs Longitudinal Incision in Myomectomy https://ClinicalTrials.gov/show/NCT03009812 Completed Ain Shams University 2018-01-31
NCT02954744 High-intensity Focused Ultrasound in Treatment of Uterine Fibroid https://ClinicalTrials.gov/show/NCT02954744 Completed Queen Mary Hospital, Hong Kong 2017-08-31
NCT02942537 Study of Volume Reduction of Uterine Fibroids After Embolization or Microwave Treatment https://ClinicalTrials.gov/show/NCT02942537 Recruiting Karolinska Institutet 2019-12-31
NCT02889848 Safety and Tolerability of Collagenase Clostridium Histolyticum (EN3835) to Treat Uterine Leiomyoma (Fibroids) https://ClinicalTrials.gov/show/NCT02889848 Completed Advance Biofactures Corporation 2018-10-05
NCT02829333 The Effect of Anesthetic Technique on VEGF-C and PGE2 https://ClinicalTrials.gov/show/NCT02829333 Completed General Hospital of Ningxia Medical University 2016-04-30
NCT02620345 Fibroids in Women of Reproductive Age and Women Pregnancy https://ClinicalTrials.gov/show/NCT02620345 Completed Triệu, Nguyễn Thị, M.D. 2015-10-31
NCT02563392 Does Preventive Uterine Artery Occlusion During Laparoscopic Myomectomy Impact on Ovarian Reserve Markers? https://ClinicalTrials.gov/show/NCT02563392 Recruiting University Hospital, Geneva 2022-05-31
NCT02654054 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women https://ClinicalTrials.gov/show/NCT02654054 Completed AbbVie 2018-01-18
NCT02520414 Symphion® System In-Office Study https://ClinicalTrials.gov/show/NCT02520414 Completed Boston Scientific Corporation 2015-03-31
NCT02472184 Optimal Order of Concurrent Office Hysteroscopy and Endometrial Biopsy https://ClinicalTrials.gov/show/NCT02472184 Completed University of South Florida 2017-03-31
NCT02470741 Pilot of Letrozole for Uterine Myomas https://ClinicalTrials.gov/show/NCT02470741 Completed University of California, San Francisco 2017-12-31
NCT02465814 Assess Safety and Efficacy of Vilaprisan in Patients With Uterine Fibroids https://ClinicalTrials.gov/show/NCT02465814 Completed Bayer 2016-10-31
NCT02425878 Ulipristal Acetate 10 mg and Asisted Reproduction https://ClinicalTrials.gov/show/NCT02425878 Completed Instituto Valenciano de Infertilidad, IVI VALENCIA 2016-05-31
NCT02410018 Safety and Effectiveness of OCL 503 in the Treatment of Women With Leiomyomata https://ClinicalTrials.gov/show/NCT02410018 Completed IMBiotechnologies Ltd. 2016-06-30
NCT02392585 Single or Triple Uterine Tourniquet at Myomectomy https://ClinicalTrials.gov/show/NCT02392585 Completed Ataturk University 2016-03-31
NCT02386137 Factors Influencing Volumetric MR-HIFU Ablation of Uterine Fibroids https://ClinicalTrials.gov/show/NCT02386137 Completed University Hospital, Bordeaux 2017-10-31
NCT02323646 Safety and Efficacy of Telapristone Acetate (Proellex®) Administered Vaginally for the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT02323646 Completed Repros Therapeutics Inc. 2017-04-06
NCT02301897 A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT02301897 Completed Repros Therapeutics Inc. 2017-06-02
NCT02228174 Sonography Guided Transcervical Ablation of Uterine Fibroids https://ClinicalTrials.gov/show/NCT02228174 Completed Gynesonics 2017-10-18
NCT02227316 Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure https://ClinicalTrials.gov/show/NCT02227316 Completed University of California, Los Angeles 2016-09-30
NCT02209545 Misoprostol for Reduction of Blood Loss During Fibroid Surgery https://ClinicalTrials.gov/show/NCT02209545 Recruiting Northwestern University 2020-08-31
NCT02147197 A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas https://ClinicalTrials.gov/show/NCT02147197 Completed Allergan 2016-03-29
NCT02147158 A Study of the Efficacy and Safety of Ulipristal Acetate Intermittent Treatment for Abnormal Uterine Bleeding Associated With Leiomyomas https://ClinicalTrials.gov/show/NCT02147158 Completed Allergan 2016-11-24
NCT02086435 Intracorporeal Versus Extracorporeal Morcellation: Clinical Efficacy and Safety Outcomes https://ClinicalTrials.gov/show/NCT02086435 Completed University Magna Graecia 2014-12-31
NCT02059954 Vaginal vs. Laparoscopic Hysterectomy https://ClinicalTrials.gov/show/NCT02059954 Completed Medical University of Graz 2016-08-31
NCT01285960 ExAblate UF V2 System for the Treatment of Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT01285960 Completed InSightec 2016-04-30
NCT02056717 Use of Dexamethasone in Uterine Artery Embolization https://ClinicalTrials.gov/show/NCT02056717 Completed Severance Hospital 2015-04-30
NCT02049242 Uterine Tourniquet at Open Myomectomy https://ClinicalTrials.gov/show/NCT02049242 Completed Ataturk University 2014-12-31
NCT01984632 Barbed Suture in Single-port Laparoscopic Myomectomy https://ClinicalTrials.gov/show/NCT01984632 Completed CHA University 2014-12-31
NCT01946178 Clinical Study of the Mirabilis High-Intensity Focused Ultrasound System for Non-Invasive Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT01946178 Completed Mirabilis Medica, Inc. 2015-05-31
NCT01937104 ONSD According to the Position During Laparoscopy https://ClinicalTrials.gov/show/NCT01937104 Completed Chosun University Hospital 2014-09-30
NCT01873378 GnRH Agonist Pretreatment in Hysteroscopic Myomectomy https://ClinicalTrials.gov/show/NCT01873378 Completed Azienda Ospedaliera S. Maria della Misericordia 2015-08-31
NCT01861015 Vasopressin Versus Epinephrine in Myomectomy https://ClinicalTrials.gov/show/NCT01861015 Completed CHA University 2014-03-31
NCT01852734 Uterine Fibroid Embolization- Long Term Follow up and Technical Perspectives https://ClinicalTrials.gov/show/NCT01852734 Completed Odense University Hospital 2016-04-30
NCT01840124 Uterine Leiomyoma Treatment With Radiofrequency Ablation https://ClinicalTrials.gov/show/NCT01840124 Completed University of California, San Francisco 2020-01-31
NCT01817530 Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF) https://ClinicalTrials.gov/show/NCT01817530 Completed AbbVie 2015-06-30
NCT01750008 Laparoscopic Uterine Sparing Techniques Outcomes and Reinterventions https://ClinicalTrials.gov/show/NCT01750008 Completed Acessa Health, Inc. 2013-09-30
NCT01745432 Assessment of the Manageability and Safety of ADBLOCK Adhesion Barrier System in Laparoscopic Gynaecological Surgery https://ClinicalTrials.gov/show/NCT01745432 Completed Terumo Europe N.V. 2015-08-31
NCT01739621 Safety, Pharmacokinetics and Efficacy of Proellex® (Telapristone Acetate) Administered Vaginally in the Treatment of Premenopausal Women With Uterine Fibroids Who Have Completed ZPV-200 https://ClinicalTrials.gov/show/NCT01739621 Completed Repros Therapeutics Inc. 2014-04-30
NCT01715597 Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma https://ClinicalTrials.gov/show/NCT01715597 Completed Seoul National University Hospital 2017-10-31
NCT01631903 Extension of Study ZPV-200 https://ClinicalTrials.gov/show/NCT01631903 Completed Repros Therapeutics Inc. 2014-04-30
NCT01629563 PGL4001 Efficacy Assessment in Reduction of Symptoms Due to Uterine Leiomyomata https://ClinicalTrials.gov/show/NCT01629563 Completed PregLem SA 2015-01-31
NCT01588899 China Clinical Trial for Therapeutic MR-HIFU Ablation of Uterine Fibroids https://ClinicalTrials.gov/show/NCT01588899 Completed Philips Healthcare 2014-12-31
NCT01530802 Temporary Clipping of the Uterine Arteries During Laparoscopic Myomectomy https://ClinicalTrials.gov/show/NCT01530802 Completed Charite University, Berlin, Germany NA
NCT01492179 Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management. https://ClinicalTrials.gov/show/NCT01492179 Completed Örebro University, Sweden 2013-06-30
NCT01452659 Efficacy and Safety of TAK-385 in the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT01452659 Completed Takeda 2012-09-30
NCT01451424 Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids https://ClinicalTrials.gov/show/NCT01451424 Completed Repros Therapeutics Inc. 2012-12-31
NCT01441635 Safety and Efficacy Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids https://ClinicalTrials.gov/show/NCT01441635 Completed AbbVie 2013-11-30
NCT01379313 The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position https://ClinicalTrials.gov/show/NCT01379313 Completed Samsung Medical Center 2012-03-31
NCT01377519 Magnetic Resonance Guided Focused Ultrasound for Uterine Fibroids https://ClinicalTrials.gov/show/NCT01377519 Completed University of California, San Francisco 2012-09-30
NCT01369758 MyoSure Hysteroscopic Tissue Removal System Registry Study https://ClinicalTrials.gov/show/NCT01369758 Completed Hologic, Inc. 2013-05-31
NCT01338831 Phase I Study of LFA102 in Patients With Prolactin Receptor-positive Castration-resistant Prostate Cancer or Prolactin Receptor-positive Metastatic Breast Cancer https://ClinicalTrials.gov/show/NCT01338831 Completed Novartis 2014-03-31
NCT04145518 Mechanistic Characterization of Uterine Pain https://ClinicalTrials.gov/show/NCT04145518 Recruiting NorthShore University HealthSystem 2023-08-31
NCT04091529 Tailored Radiofrequency Ablation of Uterine Myomas https://ClinicalTrials.gov/show/NCT04091529 Completed International Evangelical Hospital 2019-03-01
NCT04073485 Microwave Ablation for Uterine Fibroids https://ClinicalTrials.gov/show/NCT04073485 Recruiting Chinese University of Hong Kong 2022-06-30
NCT03985449 Implementation of Uterine Fibroid Option Grid Patient Decision Aids Across Five Organizational Settings https://ClinicalTrials.gov/show/NCT03985449 Recruiting Dartmouth-Hitchcock Medical Center 2021-05-30
NCT03927651 ICG to Assess Ovarian Perfusion https://ClinicalTrials.gov/show/NCT03927651 Recruiting Northwestern University 2020-04-30
NCT03886220 A Study to Evaluate the Safety and Efficacy of Elagolix for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women https://ClinicalTrials.gov/show/NCT03886220 Recruiting AbbVie 2021-09-20
NCT03847077 Trial of a Patient Education Tool For Leiomyoma https://ClinicalTrials.gov/show/NCT03847077 Completed Loyola University 2018-10-31
NCT03751124 Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03751124 Active, not recruiting Myovant Sciences GmbH 2021-02-28
NCT03535610 Uterine Artery Embolization With Microspheres in Patients With Leiomyoma. https://ClinicalTrials.gov/show/NCT03535610 Active, not recruiting Scitech Produtos Medicos Ltda 2020-02-20
NCT03500367 Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis https://ClinicalTrials.gov/show/NCT03500367 Recruiting Peking Union Medical College Hospital 2022-06-30
NCT03476928 A Study to Assess the Safety and Efficacy of Vilaprisan in Japanese Subjects With Uterine Fibroids and Heavy Menstrual Bleeding https://ClinicalTrials.gov/show/NCT03476928 Active, not recruiting Bayer 2021-02-28
NCT03427671 OCL 500 Treatment of Women With Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT03427671 Completed IMBiotechnologies Ltd. 2019-09-03
NCT03412890 LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03412890 Active, not recruiting Myovant Sciences GmbH 2020-01-24
NCT01152112 HOME Study: Hysteroscopic Office Myomectomy Evaluation https://ClinicalTrials.gov/show/NCT01152112 Completed Hologic, Inc. 2012-01-31
NCT01142791 Safety Study of ExAblate for the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT01142791 Completed InSightec 2012-04-30
NCT01141062 Therapeutic MRI Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids https://ClinicalTrials.gov/show/NCT01141062 Completed Philips Healthcare 2011-10-31
NCT01092988 A Clinical Study to Evaluate Safety of the ExAblate 2100 UF V2 System in the Treatment of Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT01092988 Completed InSightec 2012-02-29
NCT01069094 A Study of Progenta (CDB-4124) in Pre-menopausal Women With Symptomatic Leiomyomata https://ClinicalTrials.gov/show/NCT01069094 Completed Repros Therapeutics Inc. 2005-01-31
NCT01064960 Therapeutic MRI-HIFU Ablation of Uterine Fibroids in a 3T MRI Scanner https://ClinicalTrials.gov/show/NCT01064960 Completed Philips Healthcare 2011-07-31
NCT01064128 Study of Different Pain Scores in Single-Port Access (SPA) Laparoscopic Hysterectomy Versus Conventional Laparoscopic Hysterectomy https://ClinicalTrials.gov/show/NCT01064128 Completed Samsung Medical Center 2010-12-31
NCT00995878 The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids. https://ClinicalTrials.gov/show/NCT00995878 Completed Mayo Clinic 2016-12-31
NCT00979342 Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System https://ClinicalTrials.gov/show/NCT00979342 Completed Hologic, Inc. 2010-07-31
NCT00971620 Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas With Botulinum Toxin https://ClinicalTrials.gov/show/NCT00971620 Completed National Institutes of Health Clinical Center (CC) 2014-01-09
NCT00958334 Extension Study of Proellex in Women Who Have Previously Completed Study ZPU 003 https://ClinicalTrials.gov/show/NCT00958334 Completed Repros Therapeutics Inc. 2008-10-15
NCT00897897 Therapeutic Magnetic Resonance Imaging (MRI)-Guided High Intensity Focused Ultrasound (HIFU) Ablation of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00897897 Completed Philips Healthcare 2009-12-31
NCT00891657 Post Market Study for an Adhesion Barrier Following Laparoscopic Myomectomy https://ClinicalTrials.gov/show/NCT00891657 Completed Integra LifeSciences Corporation 2009-05-31
NCT00886873 Mifepristone 10 or 5 mg for 6 Months to Treat Uterine Fibroids https://ClinicalTrials.gov/show/NCT00886873 Completed Mediterranea Medica S. L. 2009-04-30
NCT00882258 Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT00882258 Completed Repros Therapeutics Inc. 2007-03-31
NCT00881140 Efficacy Study of Vaginal Mifepristone to Treat Uterine Fibroids https://ClinicalTrials.gov/show/NCT00881140 Completed BioPro Medical Ltd 2012-05-31
NCT00874029 Laparoscopic Radiofrequency Ablation (RFA) of Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT00874029 Completed Acessa Health, Inc. 2012-01-31
NCT00839722 Fertility After Uterine Artery Embolisation for the Treatment of Leiomyomas https://ClinicalTrials.gov/show/NCT00839722 Completed Assistance Publique - Hôpitaux de Paris 2011-07-31
NCT03930069 Vasopressin Injection Versus Misoprostol During Hysteroscopic Myomectomy In Reducing Blood Loss And Operation Time. https://ClinicalTrials.gov/show/NCT03930069 Completed Zagazig University 2017-01-30
NCT00837161 Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00837161 Completed Philips Healthcare 2010-02-28
NCT04434066 Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy https://ClinicalTrials.gov/show/NCT04434066 Recruiting University of Texas Southwestern Medical Center 2021-06-30
NCT03028610 Pregnancy Outcome Following Global Fibroid Ablation Using the Acessaâ„¢ System https://ClinicalTrials.gov/show/NCT03028610 Recruiting University Women’s Hospital Tübingen 2020-12-31
NCT02925494 An Extension Study to Evaluate the Efficacy and Safety of Elagolix in Premenopausal Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT02925494 Completed AbbVie 2018-05-07
NCT02691494 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women (Replicate Study) https://ClinicalTrials.gov/show/NCT02691494 Completed AbbVie 2018-02-14
NCT03880435 HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant https://ClinicalTrials.gov/show/NCT03880435 Recruiting University Hospital, Ghent 2022-05-01
NCT03796130 Does Myomectomy for Intramural Fibroid Improve ART Outcome? https://ClinicalTrials.gov/show/NCT03796130 Recruiting Mansoura University 2021-04-30
NCT03240523 Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids https://ClinicalTrials.gov/show/NCT03240523 Active, not recruiting Bayer 2021-01-15
NCT02655237 A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT02655237 Completed Takeda 2017-05-17
NCT02655224 A Placebo-Controlled, Phase 3 Study of Relugolix (TAK-385) 40 mg in the Treatment of Pain Symptoms Associated With Uterine Fibroids https://ClinicalTrials.gov/show/NCT02655224 Completed Takeda 2017-05-16
NCT02577055 Fertility After Myomectomy Versus Uterine Artery Embolization for Symptomatic Uterine Fibroids https://ClinicalTrials.gov/show/NCT02577055 Active, not recruiting Assistance Publique - Hôpitaux de Paris 2019-11-30
NCT02293447 Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization https://ClinicalTrials.gov/show/NCT02293447 Completed University Health Network, Toronto 2016-03-31
NCT00776074 A Pharmacodynamic Study of Leuprorelin Gelatin-Free Formulation in Female Subjects With Uterine Fibroids. https://ClinicalTrials.gov/show/NCT00776074 Completed Takeda 2007-07-31
NCT00755755 PGL4001 Versus Placebo in Uterine Myomas https://ClinicalTrials.gov/show/NCT00755755 Completed PregLem SA 2010-03-31
NCT00746031 Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids https://ClinicalTrials.gov/show/NCT00746031 Completed University of Edinburgh 2010-09-30
NCT00743080 Randomized Controlled Trial (RCT)Comparing GYNAECARE MORCELLEX Versus ROTOCUT GI Tissue Morcellators https://ClinicalTrials.gov/show/NCT00743080 Completed University Magna Graecia NA
NCT00740831 PGL4001 Versus GnRH-agonist in Uterine Myomas https://ClinicalTrials.gov/show/NCT00740831 Completed PregLem SA 2010-01-31
NCT00731341 Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata https://ClinicalTrials.gov/show/NCT00731341 Completed Galil Medical, a wholly owned indirect subsidiary of Boston Scientific 2009-02-28
NCT00712595 Mifepristone for Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00712595 Completed Mediterranea Medica S. L. 2007-01-31
NCT00628901 A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE) https://ClinicalTrials.gov/show/NCT00628901 Completed Boston Scientific Corporation 2009-12-31
NCT00579475 The Effect of Mifepristone on Uterine Fibroids and Breast Tissue https://ClinicalTrials.gov/show/NCT00579475 Completed Karolinska Institutet 2007-06-30
NCT00543790 Study Evaluating PRA-027 Multiple Ascending Doses In Cycling And Postmenopausal Women https://ClinicalTrials.gov/show/NCT00543790 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2008-12-31
NCT00444704 Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 Administered to Healthy Japanese Females https://ClinicalTrials.gov/show/NCT00444704 Completed Wyeth is now a wholly owned subsidiary of Pfizer NA
NCT00365989 MR Guided Focused Ultrasound Treatment of Uterine Fibroids With Enhanced Sonication https://ClinicalTrials.gov/show/NCT00365989 Completed InSightec 2008-08-31
NCT00361036 Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlockâ„¢ Embolic Agent https://ClinicalTrials.gov/show/NCT00361036 Completed Worthington-Kirsch, Robert L., M.D. 2010-03-31
NCT00332033 Development of a Non-Invasive Treatment for Uterine Leiomyoma (Fibroids) https://ClinicalTrials.gov/show/NCT00332033 Completed National Institutes of Health Clinical Center (CC) NA
NCT00295217 MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids: Software V4.2 Validation https://ClinicalTrials.gov/show/NCT00295217 Completed InSightec NA
NCT00290251 Treatment of Uterine Fibroids With the Selective Progesterone Receptor Modulator CDB-2914 https://ClinicalTrials.gov/show/NCT00290251 Completed National Institutes of Health Clinical Center (CC) 2009-07-31
NCT00152256 A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids https://ClinicalTrials.gov/show/NCT00152256 Completed Abbott 2005-02-28
NCT00166270 MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00166270 Completed InSightec 2006-04-30
NCT00160459 A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00160459 Completed Abbott 2001-07-31
NCT00160381 A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00160381 Completed Abbott 2005-01-31
NCT00159328 Efficacy Study of Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Large Fibroids https://ClinicalTrials.gov/show/NCT00159328 Completed Imperial College London NA
NCT00156208 Safety of Treatment of Uterine Fibroids With Asoprisnil https://ClinicalTrials.gov/show/NCT00156208 Completed Abbott 2006-12-31
NCT00156195 Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00156195 Completed Abbott 2007-01-31
NCT00156182 A Long-Term Safety Study of Asoprisnil in the Treatment of Uterine Fibroids. https://ClinicalTrials.gov/show/NCT00156182 Completed Abbott 2001-12-31
NCT00156156 Study of Asoprisnil in the Treatment of Uterine Fibroids. https://ClinicalTrials.gov/show/NCT00156156 Completed Abbott 2007-02-28
NCT00152269 Treatment of Uterine Fibroids With Asoprisnil(J867) https://ClinicalTrials.gov/show/NCT00152269 Completed Abbott 2005-01-31
NCT00150644 A Study to Evaluate the Effects of Asoprisnil(J867) in Women With Uterine Fibroids Who Are Scheduled for a Hysterectomy https://ClinicalTrials.gov/show/NCT00150644 Completed Abbott 2005-05-31
NCT00131365 Magnetic Resonance (MR) Guided Focused Ultrasound Surgery of Uterine Fibroids https://ClinicalTrials.gov/show/NCT00131365 Completed InSightec 2009-01-31
NCT00100191 Emmy Trial: Uterine Artery Embolization (UAE) Versus Hysterectomy for Uterine Fibroids https://ClinicalTrials.gov/show/NCT00100191 Completed ZonMw: The Netherlands Organisation for Health Research and Development NA
NCT00044876 Treatment of Uterine Fibroids With CDB-2914, an Experimental Selective Progesterone Receptor Antagonist https://ClinicalTrials.gov/show/NCT00044876 Completed National Institutes of Health Clinical Center (CC) 2007-06-16

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04400942 Predictive Factors for Complete Myoma Resection During Hysteroscopic Myomectomy https://ClinicalTrials.gov/show/NCT04400942 Recruiting Ospedale Policlinico San Martino 2020-06-01
NCT03871868 Vitamin D Levels And Myoma Uteri https://ClinicalTrials.gov/show/NCT03871868 Completed Kanuni Sultan Suleyman Training and Research Hospital 2019-03-01
NCT02997787 New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma https://ClinicalTrials.gov/show/NCT02997787 Completed Kayseri Education and Research Hospital 2016-10-31
NCT02844920 Evaluation of Uterine Patency Following Sonography-guided Transcervical Ablation of Fibroids https://ClinicalTrials.gov/show/NCT02844920 Completed Gynesonics 2018-08-27
NCT02819609 Comparing Patient-Centered Outcomes After Treatment for Uterine Fibroids https://ClinicalTrials.gov/show/NCT02819609 Completed Quintiles, Inc. 2015-01-31
NCT00050752 Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer https://ClinicalTrials.gov/show/NCT00050752 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02495311 The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms https://ClinicalTrials.gov/show/NCT02495311 Recruiting Far Eastern Memorial Hospital 2020-12-31
NCT02123069 Vascular Function and Uterine Fibroids https://ClinicalTrials.gov/show/NCT02123069 Completed Mayo Clinic 2018-03-01
NCT02100904 Uterine Leiomyoma Treatment With Radiofrequency Ablation (ULTRA) Registry https://ClinicalTrials.gov/show/NCT02100904 Recruiting University of California, San Francisco 2025-01-31
NCT03744507 Bone Mineral Density in Women With Uterine Fibroids or Endometriosis https://ClinicalTrials.gov/show/NCT03744507 Active, not recruiting Myovant Sciences GmbH 2020-10-31
NCT01936493 Biologic Predictors of Leiomyoma Treatment Outcomes https://ClinicalTrials.gov/show/NCT01936493 Completed Mayo Clinic 2015-05-31
NCT01592903 Somatic Stem Cells in Leiomyomas? https://ClinicalTrials.gov/show/NCT01592903 Completed Igenomix 2015-12-31
NCT03349190 Impact of Esmya on Fertility to Infertile Women With Fibroids Managed With Assisted Reproduction Techniques https://ClinicalTrials.gov/show/NCT03349190 Completed ASSOCIATION POUR LE DEVELOPPEMENT EN FECONDATION IN VITRO 2018-06-30
NCT01542658 Comparison of Robot-assisted Laparoscopic Myomectomy With Traditional Laparoscopic Myomectomy https://ClinicalTrials.gov/show/NCT01542658 Completed Far Eastern Memorial Hospital 2012-02-29
NCT01468402 Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma https://ClinicalTrials.gov/show/NCT01468402 Completed Hospital Israelita Albert Einstein 2009-04-30
NCT01463462 Electronic Catheter Stethoscope https://ClinicalTrials.gov/show/NCT01463462 Completed University of South Florida 2016-04-30
NCT04279626 Surgical Outcome of Two-port Laparoscopic Myomectomy https://ClinicalTrials.gov/show/NCT04279626 Completed National Taiwan University Hospital 2019-09-23
NCT04214457 Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas https://ClinicalTrials.gov/show/NCT04214457 Recruiting Igenomix 2022-07-31
NCT04030182 Vitamin D Deficit in Women With Uterine Fibroids https://ClinicalTrials.gov/show/NCT04030182 Recruiting Instituto Mexicano del Seguro Social 2020-10-30
NCT04028986 Esmya Versus Surgery Before IVF/ICSI https://ClinicalTrials.gov/show/NCT04028986 Recruiting Universitair Ziekenhuis Brussel 2021-12-31
NCT04004884 Liver Safety Assessment During Ulipristal Acetate Treatment for Uterine Fibroids (LISA) https://ClinicalTrials.gov/show/NCT04004884 Recruiting Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau 2019-12-31
NCT03991078 Effect of Vitamin D on the Size of Fibroids in Women With Vitamin D Deficiency https://ClinicalTrials.gov/show/NCT03991078 Recruiting Fundación IVI 2020-06-25
NCT03989661 Is There a Place for Pre-operative Temporary Embolization of Uterine Fibroids https://ClinicalTrials.gov/show/NCT03989661 Active, not recruiting Groupe Hospitalier Paris Saint Joseph 2020-03-31
NCT03972917 Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy https://ClinicalTrials.gov/show/NCT03972917 Recruiting University of Campania “Luigi Vanvitelli” 2021-11-30
NCT03901404 Myomectomy Operation and Fundus Incision, Energy Modalities and Methods of Extraction https://ClinicalTrials.gov/show/NCT03901404 Active, not recruiting Kanuni Sultan Suleyman Training and Research Hospital 2021-04-01
NCT03757975 Impact of Hysterectomy on Quality of Life and Urethral Length https://ClinicalTrials.gov/show/NCT03757975 Recruiting Medical University of Lublin 2020-04-30
NCT03533907 Pregnancy Outcomes in Infertile Patients After Treatment With Ulipristal Acetate. https://ClinicalTrials.gov/show/NCT03533907 Completed Istituto Clinico Humanitas 2018-04-10
NCT03444987 The Role of Fibroblast Activation in Uterine Fibroid https://ClinicalTrials.gov/show/NCT03444987 Completed Assiut University 2019-11-01
NCT01267851 Clinical Database and Biobank of Patients With Gynecologic Neoplasms https://ClinicalTrials.gov/show/NCT01267851 Recruiting Huazhong University of Science and Technology 2019-12-30
NCT01229826 Magnetic Resonance Elastography (MRE) of Uterine Fibroids https://ClinicalTrials.gov/show/NCT01229826 Completed Mayo Clinic 2015-06-30
NCT01123603 Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata https://ClinicalTrials.gov/show/NCT01123603 Completed The Cleveland Clinic 2014-06-30
NCT00910468 Robot-Assisted Laparoscopic Myomectomy Is an Improvement Over Laparotomy in Patients With a Limited Number of Fibroids https://ClinicalTrials.gov/show/NCT00910468 Completed Ascher-Walsh, Charles, M.D. 2008-07-31
NCT00826436 Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRA-027 in Japanese Postmenopausal Women https://ClinicalTrials.gov/show/NCT00826436 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2009-03-31
NCT02580578 A Multicenter Prospective Non-Interventional Study Assessing the Management of Canadian Women With Uterine Fibroids https://ClinicalTrials.gov/show/NCT02580578 Completed Allergan 2020-01-31
NCT00339547 Risk Factors for Uterine Fibroids: A Case Control Study https://ClinicalTrials.gov/show/NCT00339547 Completed National Institutes of Health Clinical Center (CC) NA
NCT00354471 Uterine Artery Embolization for Symptomatic Fibroids https://ClinicalTrials.gov/show/NCT00354471 Completed University of Manitoba NA
NCT00341848 Postpartum Uterine Regression https://ClinicalTrials.gov/show/NCT00341848 Completed National Institutes of Health Clinical Center (CC) NA
NCT00340288 Fibroid Growth Study https://ClinicalTrials.gov/show/NCT00340288 Completed National Institutes of Health Clinical Center (CC) 2006-04-01
NCT00005095 Specimen and Data Study for Ovarian Cancer Early Detection and Prevention https://ClinicalTrials.gov/show/NCT00005095 Recruiting Northwestern University 2020-12-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03118037 Transcervical Radiofrequency Ablation of Uterine Fibroids Global Registry https://ClinicalTrials.gov/show/NCT03118037 Recruiting Gynesonics 2023-07-31
NCT02260752 Patient Centered Results for Uterine Fibroids https://ClinicalTrials.gov/show/NCT02260752 Active, not recruiting Duke University 2020-09-29
NCT04426760 Fibroids and Infertility - a Study of the Significance of Removal of Fibroids With Regard to Endometrial Receptivity https://ClinicalTrials.gov/show/NCT04426760 Recruiting Oslo University Hospital 2021-09-15